Therapy of newly diagnosed follicular lymphoma
نویسندگان
چکیده
منابع مشابه
Therapy of newly diagnosed follicular lymphoma
Newly diagnosed follicular lymphoma is relatively common and can be effectively treated with several differing approaches. Although the disease is often considered incurable, it is highly responsive to therapy when indicated. This review discusses the indications for treatment, risk stratification systems, treatment options with supporting clinical trial data, and expected therapeutic outcomes ...
متن کاملGenetic diversity of newly diagnosed follicular lymphoma
Follicular lymphoma (FL) is the second most common form of non-Hodgkin lymphoma (NHL) and often follows an indolent disease course with slow progression. However, patients may develop resistant disease; in addition, transformation to a more aggressive subtype of lymphoma occurs at a rate of 2–3% per year. FL arises from germinal center B cells and the most common molecular defect is t(14;18)(q3...
متن کاملTreatment of Newly Diagnosed and Relapsed Hodgkin Lymphoma in Children
Hodgkin lymphoma (HL) accounts for about 10% of all childhood cancers. Five-year survival rates with modern therapies are now approaching >90-95% as a consequence of its significant sensitivity to both chemotherapy and radiation. The current challenge is to determine how much therapy is needed to improve survival and how to adapt treatment to the patient to prevent these long term toxicities. T...
متن کاملBortezomib-based therapy for newly diagnosed mantle-cell lymphoma.
BACKGROUND The proteasome inhibitor bortezomib was initially approved for the treatment of relapsed mantle-cell lymphoma. We investigated whether substituting bortezomib for vincristine in frontline therapy with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) could improve outcomes in patients with newly diagnosed mantle-cell lymphoma. METHODS In this phase 3 tr...
متن کاملESMO Minimum Clinical Recommendations for diagnosis, treatment and follow-up of newly diagnosed follicular lymphoma.
• Diagnosis should always be based on a surgical specimen/ excisional lymph node biopsy providing enough material for fresh-frozen and formalin-fixed samples. To ensure adequate quality, immediate processing by an experienced pathology institute has to be guaranteed. • Fine-needle aspirations or core biopsies are inappropriate for a proper diagnosis and should only be used in the rare patients ...
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ژورنال
عنوان ژورنال: Frontiers in Oncology
سال: 2012
ISSN: 2234-943X
DOI: 10.3389/fonc.2012.00188